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R. S. Bhandari , Swati Pande , M. C. Joshi , S. M. H. Zaidi , J. M. S. Rawat , Vinod Kumar

Abstract

Control of cone worm Dioryctria abietella Denis and Schiff. Infesting cone and seed of spruce (Picea smithiana) in seed production areas was attempted. The systemic insecticides viz thimet, carbofuran, dimethoate, monocrotophos were applied at the point of drip line application in soil and through tree injection at the base of the trees in Seed Production Area (SPA) at Deoban, Kanasar Range, Chakrata Forest Division (Uttaranchal). Tree injection with monocrotophos 36 EC 100 ml with 20 cm Girth of a tree at Breast Height was found superior than the application of granular pesticides in the soil at the drip line. Tree injection could protect 86.49 per cent, cones from the attack of cone worm.

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M. C. Joshi , S. Radhakrishnan , R. Khare

Abstract

No abstract

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M. C. Joshi , C. B. S. R. Sarma

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51 grasses-22 belonging to the subfamily Panicoideae and 29 to the subfamily Pooideae are reported from certain areas of Jhunjhunu district, Rajasthan. Occurring most frequent are those of tribe Eragrosteae. The above data are compared with those of other investigated areas of the state. It is found that tribe Paniceae, in general, is dominant in the state. The grasses further categorized into habitat c1asses.

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M. C. Joshi , M. Mohan Kumar , T. Prabha , M. Dorababu , R. K. Goel

Abstract

Objective: The aim of the present study was to evaluate the status of gastric mucosal defense in pylorus-ligated (PL)-induced gastric ulceration (GU) and secretion in normal and non-insulin dependent diabetes mellitus (NIDDM) rats and to study the effect of methanolic extract of dried powder of unripe plantain banana pulp (Musa sapientum var. paradisiaca, MSE) shown to have both ulcer protective action and hypoglycemic principle in normal and NIDDM rats with concurrent gastroduodenal ulceration. Methods: NIDDM was induced in 5 days old rat pups by administering 70 mg/kg of streptozotocin intraperitoneally and blood glucose estimation was done after 12 weeks (blood glucose level >140 mg/dL and stable). Gastric ulcers were induced both in normal (NR) and NIDDM rats by 4 h PL. MSE was used in a dose of 100 mg/kg, orally (po), once daily (od) for 6 days. Standard ulcer protective drug sucralfate (SFT) and standard oral hypoglycemic agent glibenclamide (GLC) were used in a dose of 500mg/kg and 0.6 mg/kg respectively, po, od for 6 days. Results: MSE but not SFT tended to decrease blood glucose level at the ulcer protective dose used, while GLC significantly reduced it both in normal as well as in NIDDM rats. There was an increased propensity to gastric ulceration in NIDDM-PL rats compared to the normal PL rats. NIDDM rats showed a tendency to increase in acid-pepsin secretion and decrease in mucin secretion and life span of mucosal cells. Both SFT and MSE showed significant antiulcer activity against PL-GU in NR and NIDDM rats, where as GLC showed a significant effect only against PL-GU in NIDDM rats. Both MSE (having little or no effect on offensive acid-pepsin secretion) and SFT (caused decrease in pepsin secretion) significantly increased the defensive factors like mucin secretion and life span of mucosal cells both in NR-PL and NIDDM-PL rats while, GLC reversed the above parameters only in NIDDM-PL rats near to the normal control level. Conclusion: The study thus indicated that diabetes do affect both the offensive and defensive gastric mucosal factors and correction of either blood sugar level or promotion of defensive mucosal factors do overcome the damage induced by diabetes vis a vis gastric ulceration. Plantain banana by virtue of its having both ulcer protective activity and hypoglycemic principle showed better effect than SFT or GLC alone in NIDDM rats.

Keywords

NIDDM, Gastric Ulcer, Acid-pepsin, Mucin, Cell Shedding, Plantain Banana

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V. S. Bhende ¹, M. C. Joshi ¹, P. R. Melmane ¹, D. V. Mhambrey ¹, V. C. Palekar ¹, Y. A. Parikh ¹, A. B. Parulkar ¹, D. G. Vaze ¹

Affiliations
1 Bombay, IN

Abstract

No Abstract.

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